Programme

• FRIDAY
• SATURDAY
• POSTERS

• Friday, 9 September
  12:00	Registration and welcome mingling cocktail
  14:00-14:10	Opening
  14:10-15:10	DNA and RNA stability Chair: Alessandra Montecucco (Pavia)
  	Morena Catillo (Pavia) Splicing of transcripts for splicing factor SRSF1 is finely tuned in response to cell metabolism
  	Cristina Mazzoni (Rome) RNA oxidation and ageing in mRNA degradation mutants of S. cerevisiae
  	Annapina Russo (Naples) Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53
  15:10-16:10	Cell death and metabolism Chair: Valter Longo (Los Angeles, CA, USA)
  	Nicoletta Guaragnella (Bari) Cell fate decision in yeast: within and between glucose sensing, Hog1 SAPK and mitochondrial retrograde pathways
  	Enzo Martegani (Milan) Accumulation of activated Ras in mitochondria and apoptosis
  	Flavia Cuviello (Potenza) Modulation of mitochondrial pyruvate carrier expression in HEK293 and HepG2 cells
  16:10-16:30	Coffee break and poster viewing
  16:30-17:30	Plenary Lecture Valter Longo (Los Angeles, CA, USA) Nutrient signaling, cellular protection and regeneration, and healthspan
  17:30-19:00	Poster Session
  19:00-20:00	Host-pathogen interaction Chair: Cristina Mazzoni (Rome)
  	Rosanna Salvia (Potenza) The multifunctional polydnavirus ANK1 protein: new insights for apoptotis pathway
  	Luisa Rubino (Bari) Carnation Italian ringspot virus p36 expression enhances necrotic cell death in response to acetic acid in Saccharomyces cerevisiae
  	Gerarda Grossi (Potenza) The role of apoptosis in parasitism: the case of Aphidius ervi
  20:30	Social Dinner

• Saturday, 10 September
  9:00-9:40	Cell stress and chaperones Chair: Enzo Martegani (Milan)
  	Grazia Tamma (Bari) The abundance of the vasopressin regulated water channel AQP2 is controlled by the E3-ligase CHIP via HSP70, as possible anchoring protein for the E3-ligase MDM2
  	Mark Woodford (Syracuse, NY, USA) The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
  9:40-10:40	Environmental stress and anti-stress agents Chair: Francesca Zito (Palermo)
  	Fiorenza Minervini (Bari) Influence of digestion process on antioxidant activity induced by artichoke and grape polyphenols in human intestinal model
  	Viviana di Giacomo (Chieti) Oxidative stress, apoptosis and survival in human gingival fibroblasts exposed to e-cigarette fluids
  	Mariarita Stirpe (Rome) Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells
  10:40-11:00	Coffee break
  11:00-12:00	Cell stress and disease Chair: Mark Woodford (Syracuse, NY, USA)
  	Alessandra Stacchiotti (Brescia) Sirtuin 1 downregulation in obese mice: a multi-organ stress study
  	Apollonia Tullo (Bari) TRIM8 role in the crosstalk between N-MYC-miR17 family pathway and p53 tumour suppressor protein in chemo-resistant tumours
  	Manuela Loi (Bologna) Barrier-to-Autointegration Factor (BAF) evaluation during DNA-damage response
  12:10-12:40	Lecture in memory of Valeria Matranga Francesca Zito (Palermo) Valeria Matranga’s heritage: the sea urchin, a successful animal model
  12:40-13:00	Concluding remarks - Winner of the F. Ritossa award announced
  13:00	Cocktail with regional specialities

• The poster's maximum size is 70 x 100 cm (width x height).

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  P.1  Giovannella Bruscalupi (Rome)
  Sirtuin SRT2 mediates DNA damage response by modulating glutamate dehydrogenase activity in Arabidopsis thaliana
  
  P.2  Silvia Codenotti (Brescia)
  Erastin is a strong inducer of ferroptosis in human rhabdomyosarcoma cell lines 
  
  P.3  Agnieszka Felczykowska (Gdansk, Poland)
  Effect of usnic acid synthetic analogs on cancer cells
  
  P.4  Lucia Maita (Pavia)
  Chronic replication stress impacts on cell morphology and adhesion
  
  P.5  Daniela Pignataro (Pavia)
  DNA damage response induced by mitochondrial-driven oxidative stress in Parkinson’s disease cell model system
  
  P.6  Giulia Russo (Naples)
  rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS upon 5-FU treatment
  
  P.7  Roberta Russo (Palermo)
  Response of the AP-1 transcription factor to metals treatment, in P. lividus sea urchin embryos
  
  P.8  Sofia Scomazzon (Rome)
  Role of zinc-finger AN1-type domain-2a gene in human melanoma cell survival
  
  P.9  Giuseppe Sirago (Bari)
  Protection exerted by growth hormone secretagogues towards mitochondrial parameters analyzed in a rat model of cachexia
  
  P.10  Giulia Stamerra (Milan)
  DNA damage checkpoint deficiency and oxidative stress: implications for cell survival